SCHEMBL26632629

SCHEMBL26632629

CNC(=O)COc1cc2cc(Nc3nc(N4CCNCC4)ncc3Cl)cc(OC)c2n(C)c1=O

nearest known ligand 0.77

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 13/20 0.77
▸ CHRM4 P08173 1/20 0.77
▸ BCL6B Q8N143 1/20 0.77
▸ NCOR2 Q9Y618 4/20 0.58
▸ MELK Q14680 1/20 0.57
▸ ROCK2 O75116 3/20 0.44
▸ ROCK1 Q13464 2/20 0.44
▸ HDAC3 O15379 1/20 0.44
▸ HDAC1 Q13547 1/20 0.44
▸ HDAC2 Q92769 1/20 0.44
▸ ALK Q9UM73 2/20 0.40
▸ LRRK2 Q5S007 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22932325 0.91 BCL6 (0.86) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL20284171 0.90 BCL6 (0.83) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL25228543 0.89 BCL6 (0.82) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL30486070 0.89 BCL6 (0.82) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL20284173 0.89 BCL6 (0.75) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL30713709 0.89 BCL6 (0.85) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL20284550 0.89 BCL6 (0.85) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL25223209 0.88 BCL6 (0.79) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL20284174 0.87 BCL6 (1.00) BCL6CHRM4BCL6BNCOR2MELK
SCHEMBL22932326 0.87 BCL6 (1.00) BCL6CHRM4BCL6BNCOR2MELK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127909-A1 Compositions, Systems, and Methods for Modulating a Target Gene THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-04-24 — — US disclosed
EP-4518903-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR MODULATING A TARGET GENE The Board of Trustees of the Leland Stanford Junior University (US) 2025-03-12 — — EP disclosed
CN-119486762-A Compositions, systems, and methods for modulating a target gene 小利兰·斯坦福大学托管委员会 2025-02-18 — — CN disclosed
WO-2023215311-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR MODULATING A TARGET GENE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-11-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127909-A1 Compositions, Systems, and Methods for Modulating a Target Gene MYCBP, SNRPE, RPRD2 BCL6 591/4885CHRM4 4126/4885BCL6B 888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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