Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011651 | 0.86 | MEN1 (0.54) | NAMPTTPSAB1TPSD1TPSG1PRSS1 | |
| SCHEMBL26633836 | 0.83 | NAMPT (0.50) | NAMPTPRMT3ALDH1A1 | |
| SCHEMBL26633874 | 0.83 | SMN1; SMN2 (0.60) | NAMPTROCK2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL24011183 | 0.80 | NAMPT (0.59) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL24011279 | 0.78 | EPHX1 (0.56) | EPHX2NR1H4HDAC1HDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31753796 | 0.77 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL26633804 | 0.77 | NAMPT (0.56) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL26633900 | 0.77 | NAMPT (0.46) | NAMPTPRMT3 | |
| SCHEMBL24011099 | 0.76 | CYP2C9 (0.49) | NAMPTALDH1A1 | |
| SCHEMBL12735893 | 0.76 | MAOB (0.58) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | NAMPT 1/4885TPSAB1 902/4885TPSD1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.