Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634168 | 1.00 | LMNA (0.53) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26633844 | 1.00 | LMNA (0.53) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30288085 | 1.00 | LMNA (0.53) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26764112 | 0.92 | SMN1; SMN2 (0.52) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011343 | 0.91 | LMNA (0.55) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26633877 | 0.91 | NPC1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2ADAM17 | |
| SCHEMBL26633709 | 0.86 | NPC1 (0.52) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011598 | 0.82 | SMN1; SMN2 (0.57) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011472 | 0.81 | NPC1 (0.58) | MAPTNPC1RAB9ASMN1; SMN2ADAM17 | |
| SCHEMBL30306659 | 0.79 | NPSR1 (0.56) | NPC1RAB9ASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | LMNA 1650/4885MAPT 582/4885NPC1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.