SCHEMBL26634654

SCHEMBL26634654

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nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.37
▸ FABP4 P15090 1/20 0.37
▸ GAA P10253 1/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ USP2 O75604 1/20 0.33
▸ KMT2A Q03164 2/20 0.32
▸ FOLH1 Q04609 1/20 0.32
▸ MITF O75030 1/20 0.32
▸ KLF5 Q13887 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26634655 1.00 FABP3 (0.37) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21383848 1.00 FABP3 (0.37) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL26746697 0.88 KMT2A (0.32) L3MBTL1ALDH1A1KMT2AFOLH1
SCHEMBL26746691 0.88 KMT2A (0.32) L3MBTL1ALDH1A1KMT2AFOLH1
SCHEMBL24795884 0.86 USP2 (0.37) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389230 0.86 USP2 (0.37) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL24796027 0.84 CYP1A2 (0.36) L3MBTL1ALDH1A1KMT2AMITFLMNA
SCHEMBL24796675 0.84 HPGD (0.43) GAAL3MBTL1ALDH1A1KMT2AMITF
SCHEMBL24796626 0.84 L3MBTL1 (0.38) FABP3FABP4GAAL3MBTL1ALDH1A1
SCHEMBL21389372 0.84 L3MBTL1 (0.38) FABP3FABP4GAAL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
CN-112236161-A Modulators of G protein-coupled receptors 卡莫特治疗学股份有限公司 2021-01-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR FABP3 666/4885FABP4 1047/4885GAA 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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