Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 14/20 | 0.77 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.71 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26623574 | 0.93 | P2RX1 (0.67) | P2RX1P2RX7P2RX4RXFP1TMPRSS4 | |
| SCHEMBL30597868 | 0.90 | P2RX1 (0.64) | P2RX1P2RX7P2RX4RXFP1TMPRSS4 | |
| SCHEMBL12544169 | 0.88 | RXFP1 (0.88) | P2RX1RXFP1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3278266 | 0.87 | P2RX1 (1.00) | P2RX1P2RX7P2RX4RXFP1TMPRSS4 | |
| SCHEMBL127962 | 0.83 | P2RX1 (1.00) | P2RX1P2RX7P2RX4TMPRSS4MEN1 | |
| SCHEMBL10797383 | 0.83 | P2RX1 (0.73) | P2RX1P2RX7P2RX4RXFP1TMPRSS4 | |
| SCHEMBL16674476 | 0.83 | RXFP1 (0.78) | P2RX1RXFP1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL15528828 | 0.83 | RXFP1 (1.00) | RXFP1SMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL29891420 | 0.82 | P2RX1 (0.77) | P2RX1P2RX7P2RX4RXFP1TMPRSS4 | |
| SCHEMBL5666099 | 0.82 | P2RX1 (1.00) | P2RX1P2RX7P2RX4RXFP1TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | P2RX1 565/4885P2RX7 453/4885P2RX4 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.