Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.52 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.45 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.45 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.45 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.45 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.45 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.45 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.45 |
| ▸ | GIPR | P48546 | 3/20 | 0.43 |
| ▸ | GCG | P01275 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13800661 | 0.93 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2663509 | 0.86 | GCGR (0.46) | GCGRGIPR | |
| SCHEMBL13800659 | 0.86 | GCGR (0.55) | GCGRGIPRGCG | |
| SCHEMBL2663501 | 0.81 | GCGR (0.48) | GCGRGIPRGCG | |
| SCHEMBL4088382 | 0.81 | GCGR (0.60) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2652692 | 0.81 | GCGR (0.54) | GCGRGIPRGCG | |
| SCHEMBL2663502 | 0.81 | GCGR (0.48) | GCGRGIPR | |
| SCHEMBL2652693 | 0.81 | GCGR (0.54) | GCGRGIPRGCG | |
| SCHEMBL2663245 | 0.81 | GCGR (0.53) | GCGRGIPRGCG | |
| SCHEMBL4085577 | 0.80 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | GLP1R, GPR119, GCGR | GCGR 3/4885ADCY6 956/4885ADCY3 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.