Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 7/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540244 | 1.00 | XDH (0.46) | XDHERN1ALOX5APFEN1TDP1 | |
| SCHEMBL30540236 | 0.85 | ALOX5AP (0.43) | ERN1ALOX5APFEN1ALDH1A1 | |
| SCHEMBL26635226 | 0.85 | ALOX5AP (0.43) | ERN1ALOX5APFEN1ALDH1A1 | |
| SCHEMBL30540206 | 0.84 | ERN1 (0.41) | XDHERN1ALOX5APFEN1ACLY | |
| SCHEMBL30540254 | 0.84 | FEN1 (0.54) | ALOX5APFEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL26635272 | 0.84 | ERN1 (0.41) | XDHERN1ALOX5APFEN1ACLY | |
| SCHEMBL26635214 | 0.84 | FEN1 (0.54) | ALOX5APFEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL30540281 | 0.83 | XDH (0.49) | XDHERN1ALOX5APFEN1TDP1 | |
| SCHEMBL26635302 | 0.83 | XDH (0.49) | XDHERN1ALOX5APFEN1TDP1 | |
| SCHEMBL30540241 | 0.83 | XDH (0.51) | XDHERN1ALOX5APFEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208151-A1 | USP INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION | 北京华森英诺生物科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |