SCHEMBL26635822

SCHEMBL26635822

CCOC(=O)C(Cc1ccccc1)NC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.55
ELANE P08246 1/20 0.50
POLB P06746 1/20 0.50
HPRT1 P00492 1/20 0.50
TP53 P04637 1/20 0.49
GAA P10253 1/20 0.49
RAB9A P51151 1/20 0.49
ATM Q13315 1/20 0.49
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
TACR1 P25103 1/20 0.48
ALDH1A1 P00352 1/20 0.48
THRB P10828 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2622202 0.89 ATM (0.60) POLBGAARAB9AATMALDH1A1
SCHEMBL26635816 0.86 POLB (0.46) POLBGAARAB9AATMTACR1
SCHEMBL26635813 0.86 BIRC2 (0.51) POLBALDH1A1TSHR
SCHEMBL20208583 0.85 EPHX2 (0.49) GAAALDH1A1TSHR
SCHEMBL25796815 0.85 ATM (0.49) POLBATMALDH1A1THRBCYP2C9
SCHEMBL15343891 0.83 MMP8 (0.59) MMP8ELANEPOLBHPRT1TP53
SCHEMBL4765072 0.83 MMP8 (0.59) MMP8ELANEPOLBHPRT1TP53
SCHEMBL27464748 0.83 MMP8 (0.59) MMP8ELANEPOLBHPRT1TP53
SCHEMBL8966036 0.83 MMP8 (0.59) MMP8ELANEPOLBHPRT1TP53
SCHEMBL6322057 0.83 MMP8 (0.59) MMP8ELANEPOLBHPRT1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES MIRACURE BIOTECHNOLOGY LTD (CN) 2023-10-26 US disclosed
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES MIRACURE BIOTECHNOLOGY LTD (CN) 2023-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES PNP, MTAP, TYMP MMP8 959/4885ELANE 1975/4885POLB 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.