Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 11/20 | 0.46 |
| ▸ | ADCYAP1R1 | P41586 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072187 | 0.86 | GCGR (0.45) | POLBGCGRADCYAP1R1 | |
| SCHEMBL2664172 | 0.85 | GCGR (0.46) | GCGRADCYAP1R1 | |
| SCHEMBL9072413 | 0.84 | GCGR (0.46) | GCGRADCYAP1R1 | |
| SCHEMBL2664448 | 0.83 | ADCYAP1R1 (0.53) | GCGRADCYAP1R1 | |
| SCHEMBL9072408 | 0.83 | ADCYAP1R1 (0.44) | GCGRADCYAP1R1 | |
| SCHEMBL9072175 | 0.83 | GCGR (0.46) | GCGRADCYAP1R1 | |
| SCHEMBL2664287 | 0.83 | GCGR (0.44) | GCGRADCYAP1R1 | |
| SCHEMBL9072414 | 0.83 | ADCYAP1R1 (0.48) | GCGRADCYAP1R1 | |
| SCHEMBL9072172 | 0.81 | ADCYAP1R1 (0.44) | GCGRADCYAP1R1 | |
| SCHEMBL2664048 | 0.81 | ADCYAP1R1 (0.49) | GCGRADCYAP1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |