SCHEMBL2664448

SCHEMBL2664448

CC1Oc2cc(/C=N/NC(=O)c3ccc(O)c(Cl)c3)cc(/C=C/COc3ccccc3)c2O1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADCYAP1R1 P41586 8/20 0.53
GCGR P47871 12/20 0.46
SPHK2 Q9NRA0 1/20 0.42
SPHK1 Q9NYA1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9072414 0.92 ADCYAP1R1 (0.48) ADCYAP1R1GCGR
SCHEMBL9072413 0.87 GCGR (0.46) ADCYAP1R1GCGR
SCHEMBL9072408 0.86 ADCYAP1R1 (0.44) ADCYAP1R1GCGR
SCHEMBL9072172 0.86 ADCYAP1R1 (0.44) ADCYAP1R1GCGR
SCHEMBL2664287 0.86 GCGR (0.44) ADCYAP1R1GCGR
SCHEMBL2664048 0.85 ADCYAP1R1 (0.49) ADCYAP1R1GCGR
SCHEMBL2664172 0.84 GCGR (0.46) ADCYAP1R1GCGR
SCHEMBL9072410 0.84 ADCYAP1R1 (0.43) ADCYAP1R1GCGR
SCHEMBL2664045 0.83 AGTR1 (0.51) ADCYAP1R1GCGR
SCHEMBL9072409 0.83 ADCYAP1R1 (0.46) ADCYAP1R1GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 WO disclosed