Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649803 | 0.85 | KDM4C (0.52) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL27516798 | 0.84 | KDM4C (0.60) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL2649081 | 0.81 | KDM4C (0.49) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL31120330 | 0.80 | KCNA5 (0.58) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL30516905 | 0.78 | KDM4C (0.47) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL30516899 | 0.78 | KDM4C (0.47) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL30516906 | 0.78 | KDM4C (0.47) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL30148867 | 0.77 | KDM4C (0.55) | KDM4CKCNA5SCN5AL3MBTL1RAB9A | |
| SCHEMBL7651001 | 0.76 | KDM4C (0.51) | KDM4CMEN1KMT2AALDH1A1SLC6A4 | |
| SCHEMBL772902 | 0.76 | KDM4C (0.53) | KDM4CKCNA5SCN5AL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |