Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516798 | 0.78 | KDM4C (0.60) | KDM4CBCHESLC6A4KMT2AMEN1 | |
| SCHEMBL10679113 | 0.78 | KDM4C (0.53) | KDM4CKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2664069 | 0.76 | KDM4C (0.52) | KDM4CSLC6A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL30148867 | 0.76 | KDM4C (0.55) | KDM4CSLC6A4KMT2AMEN1 | |
| SCHEMBL2649803 | 0.76 | KDM4C (0.52) | KDM4CKMT2AMEN1 | |
| SCHEMBL7648183 | 0.76 | KDM4C (0.49) | KDM4CHPGDLMNAKMT2AHTR2A | |
| SCHEMBL772902 | 0.75 | KDM4C (0.53) | KDM4CKMT2AMEN1ALDH1A1CYP2A13 | |
| SCHEMBL7690214 | 0.75 | KDM4C (0.53) | KDM4CLMNAKMT2AMEN1CYP2A13 | |
| SCHEMBL28990029 | 0.75 | HPGD (0.56) | SLC6A4HPGDLMNAKMT2AHTT | |
| SCHEMBL6879618 | 0.74 | KDM4C (0.58) | KDM4CKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486153-B1 | Phenylindole derivatives as 5-HT2A receptor ligands | MERCK SHARP & DOHME LTD. | 2002-11-26 | — | — | US | disclosed |
| WO-1999011619-A1 | PHENYLINDOLE DERIVATIVES AS 5-HT2A RECEPTOR LIGANDS | MERCK SHARP & DOHME LIMITED (GB) | 1999-03-11 | — | — | WO | disclosed |