Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754171 | 0.86 | CRBN (0.66) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24207199 | 0.86 | CRBN (0.60) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30817364 | 0.84 | CRBN (0.57) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24206573 | 0.81 | CRBN (0.55) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24207321 | 0.81 | CRBN (0.55) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24206842 | 0.81 | CRBN (0.62) | CRBNDDB1POLBGSPT1CYP19A1 | |
| SCHEMBL24206598 | 0.80 | CRBN (0.54) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL8183366 | 0.80 | CRBN (0.70) | CRBNDDB1POLBCYP19A1 | |
| SCHEMBL24207005 | 0.79 | CRBN (0.52) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25091748 | 0.79 | CRBN (0.60) | CRBNDDB1POLBGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |