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SCHEMBL2664211

SCHEMBL2664211

COc1cc(/C=N/NC(=O)c2ccc(O)c(Cl)c2)cc(-c2ccccc2)c1OCCNC1CCCc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GCGR P47871 12/20 0.55
▸ ADCYAP1R1 P41586 6/20 0.55
▸ POLB P06746 2/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9072019 0.83 GCGR (0.64) GCGRADCYAP1R1
SCHEMBL9072191 0.80 GCGR (0.85) GCGRADCYAP1R1POLBALDH1A1LMNA
SCHEMBL2664104 0.79 GCGR (0.62) GCGR
SCHEMBL2664213 0.79 ADCYAP1R1 (0.64) GCGRADCYAP1R1POLBALDH1A1LMNA
SCHEMBL2664210 0.79 GCGR (0.62) GCGRADCYAP1R1POLBALDH1A1LMNA
SCHEMBL9072100 0.79 ADCYAP1R1 (0.63) GCGRADCYAP1R1POLBALDH1A1LMNA
SCHEMBL2664209 0.79 ADCYAP1R1 (0.63) GCGRADCYAP1R1POLBALDH1A1LMNA
SCHEMBL2663668 0.78 ADCYAP1R1 (0.62) GCGRADCYAP1R1POLBALDH1A1LMNA
SCHEMBL9072098 0.78 ADCYAP1R1 (0.62) GCGRADCYAP1R1POLBALDH1A1LMNA
SCHEMBL2663661 0.78 ADCYAP1R1 (0.62) GCGRADCYAP1R1POLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 — — WO disclosed