Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.85 |
| ▸ | ADCYAP1R1 | P41586 | 6/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663669 | 0.95 | GCGR (0.77) | GCGRADCYAP1R1POLBMAPTMEN1 | |
| SCHEMBL9072184 | 0.92 | GCGR (1.00) | GCGRADCYAP1R1OPRM1POLBMAPT | |
| SCHEMBL2664214 | 0.85 | GCGR (0.63) | GCGRADCYAP1R1POLBMAPTKMT2A | |
| SCHEMBL9072102 | 0.85 | GCGR (0.62) | GCGRADCYAP1R1MEN1KMT2AALDH1A1 | |
| SCHEMBL2663663 | 0.85 | GCGR (0.62) | GCGRADCYAP1R1POLBMAPTKMT2A | |
| SCHEMBL2663670 | 0.84 | GCGR (0.61) | GCGRADCYAP1R1POLBMAPTMEN1 | |
| SCHEMBL2664215 | 0.84 | GCGR (0.61) | GCGRADCYAP1R1POLBMAPTMEN1 | |
| SCHEMBL2664211 | 0.80 | GCGR (0.55) | GCGRADCYAP1R1POLBMAPTMEN1 | |
| SCHEMBL9072180 | 0.80 | GCGR (0.77) | GCGROPRM1 | |
| SCHEMBL2664210 | 0.79 | GCGR (0.62) | GCGRADCYAP1R1POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |