Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HRAS | P01112 | 6/20 | 0.48 |
| ▸ | ESR1 | P03372 | 6/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516482 | 0.92 | HRAS (0.46) | ALDH1A1HRASESR1ESR2TOP1 | |
| SCHEMBL26643327 | 0.88 | HRAS (0.53) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL26643379 | 0.86 | HRAS (0.50) | ALDH1A1HRASESR1ESR2TOP1 | |
| SCHEMBL26643173 | 0.86 | HRAS (0.50) | ALDH1A1HRASESR1ESR2TOP1 | |
| SCHEMBL26643222 | 0.86 | HRAS (0.56) | HRASESR1ESR2TOP1POLB | |
| SCHEMBL26643161 | 0.85 | HRAS (0.49) | ALDH1A1HRASESR1ESR2TOP1 | |
| SCHEMBL26643427 | 0.84 | HRAS (0.48) | ALDH1A1HRASESR1ESR2TOP1 | |
| SCHEMBL2399965 | 0.84 | LMNA (0.54) | ALDH1A1POLBKMT2ASMN1; SMN2LMNA | |
| SCHEMBL2398657 | 0.84 | LMNA (0.54) | ALDH1A1POLBKMT2ASMN1; SMN2LMNA | |
| SCHEMBL26643272 | 0.84 | HRAS (0.52) | HRASESR1ESR2TOP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313546-A1 | NUCLEIC ACID BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2025-10-09 | — | — | US | disclosed |
| EP-4522588-A1 | NUCLEIC ACID BINDERS | University of Strathclyde (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218194-A1 | NUCLEIC ACID BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2023-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313546-A1 | NUCLEIC ACID BINDERS | ZFR, NSUN3, POLI | ALDH1A1 3362/4885HRAS 830/4885ESR1 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.