SCHEMBL26643182

SCHEMBL26643182

COc1cccc(/C=C/c2ccc(C(=O)O)cn2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.54
BCHE P06276 1/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NPC1 O15118 1/20 0.52
HSP90AA1 P07900 1/20 0.52
ECE2 P0DPD6 1/20 0.52
AGTR1 P30556 1/20 0.52
FOS P01100 1/20 0.51
JUN P05412 1/20 0.51
CYP1A1 P04798 2/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP1B1 Q16678 2/20 0.51
CYP3A4 P08684 1/20 0.51
RELA Q04206 1/20 0.50
ALDH1A1 P00352 2/20 0.48
NFE2L2 Q16236 2/20 0.48
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31516525 1.00 MAOB (0.54) MAOBBCHEMEN1KMT2ANPC1
SCHEMBL26643224 0.88 MAOB (0.53) MAOBBCHEMEN1KMT2ANPC1
SCHEMBL31516495 0.88 MAOB (0.53) MAOBBCHEMEN1KMT2ANPC1
SCHEMBL2659126 0.87 AKR1C3 (0.51) MEN1KMT2ANPC1
SCHEMBL2400178 0.83 MAPT (0.64) MAOBBCHEMEN1KMT2ANPC1
SCHEMBL2400180 0.83 MAPT (0.64) MAOBBCHEMEN1KMT2ANPC1
SCHEMBL2400847 0.83 RELA (0.68) MAOBBCHEMEN1KMT2AFOS
SCHEMBL2400852 0.83 RELA (0.68) MAOBBCHEMEN1KMT2AFOS
SCHEMBL2400795 0.82 BCHE (0.68) MAOBBCHEMEN1KMT2ANPC1
SCHEMBL2400804 0.82 BCHE (0.68) MAOBBCHEMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313546-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2025-10-09 US disclosed
EP-4522588-A1 NUCLEIC ACID BINDERS University of Strathclyde (GB) 2025-03-19 EP disclosed
WO-2023218194-A1 NUCLEIC ACID BINDERS UNIVERSITY OF STRATHCLYDE (GB) 2023-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313546-A1 NUCLEIC ACID BINDERS ZFR, NSUN3, POLI MAOB 4686/4885BCHE 4578/4885MEN1 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.