Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 8/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622304 | 1.00 | JAK3 (0.42) | JAK3EGFRBTKBRD4CREBBP | |
| SCHEMBL26645701 | 0.88 | JAK1 (0.43) | JAK3BTKBRD4CREBBPTRPV1 | |
| SCHEMBL30623059 | 0.88 | JAK1 (0.43) | JAK3BTKBRD4CREBBPTRPV1 | |
| SCHEMBL30622385 | 0.88 | JAK3 (0.43) | JAK3EGFRBTKTEAD1 | |
| SCHEMBL26644879 | 0.88 | JAK3 (0.43) | JAK3EGFRBTKTEAD1 | |
| SCHEMBL30622359 | 0.84 | JAK3 (0.40) | JAK3EGFRBTK | |
| SCHEMBL26644930 | 0.84 | JAK3 (0.40) | JAK3EGFRBTK | |
| SCHEMBL30622404 | 0.83 | JAK3 (0.41) | JAK3BTK | |
| SCHEMBL26644850 | 0.83 | JAK3 (0.41) | JAK3BTK | |
| SCHEMBL30622339 | 0.82 | CSNK1E (0.46) | JAK3EGFRBTKCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | claimed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |