Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645524 | 0.84 | MKNK1 (0.52) | CSNK1ECSNK1DNUDT1TRPC3TRPC6 | |
| SCHEMBL26644832 | 0.83 | CSNK1E (0.40) | EGFRCSNK1ECSNK1DGRM5 | |
| SCHEMBL26644851 | 0.82 | CSNK1E (0.41) | EGFRCSNK1ECSNK1D | |
| SCHEMBL30622308 | 0.82 | CSNK1E (0.41) | EGFRCSNK1ECSNK1D | |
| SCHEMBL26645459 | 0.82 | CSNK1E (0.41) | EGFRCSNK1ECSNK1D | |
| SCHEMBL30622362 | 0.80 | JAK3 (0.43) | EGFRTRPC3TRPC6ERBB2MKNK1 | |
| SCHEMBL26644953 | 0.79 | BTK (0.40) | EGFRCSNK1ECSNK1DGRM5ERBB2 | |
| SCHEMBL30622390 | 0.79 | CSNK1E (0.41) | EGFRCSNK1E | |
| SCHEMBL26644937 | 0.78 | CSNK1D (0.43) | EGFRCSNK1ECSNK1DKDR | |
| SCHEMBL26644818 | 0.78 | CREBBP (0.43) | EGFRCSNK1ECSNK1DERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | claimed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | claimed |
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |