Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645717 | 0.86 | MKNK1 (0.55) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26645116 | 0.84 | CYP3A4 (0.45) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26644971 | 0.84 | EGFR (0.42) | MKNK1NUDT1CSNK1ECSNK1DGRM5 | |
| SCHEMBL30622820 | 0.83 | CYP3A4 (0.43) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26645098 | 0.83 | CYP3A4 (0.43) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26645199 | 0.83 | JAK2 (0.43) | CSNK1ECSNK1DPRKCI | |
| SCHEMBL26645791 | 0.81 | GALR2 (0.46) | MKNK1CSNK1ECSNK1DALK | |
| SCHEMBL30623109 | 0.81 | GALR2 (0.46) | MKNK1CSNK1ECSNK1DALK | |
| SCHEMBL26645230 | 0.81 | BUB1 (0.47) | CSNK1ECSNK1D | |
| SCHEMBL26645254 | 0.80 | MAPT (0.48) | MKNK1GPR119CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |