Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 5/20 | 0.63 |
| ▸ | GCK | P35557 | 10/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647547 | 0.88 | GCK (0.66) | FFAR2GCKKCNH2CASR | |
| SCHEMBL2651336 | 0.86 | GCK (0.59) | FFAR2GCKKCNH2CASR | |
| SCHEMBL9071103 | 0.83 | GCK (0.73) | FFAR2GCKKCNH2 | |
| SCHEMBL2646757 | 0.82 | FFAR2 (0.91) | FFAR2GCKKCNH2 | |
| SCHEMBL2644739 | 0.81 | GCK (0.76) | FFAR2GCKKCNH2 | |
| SCHEMBL27480871 | 0.81 | GCK (0.69) | FFAR2GCKKCNH2 | |
| SCHEMBL27481667 | 0.81 | GCK (0.69) | FFAR2GCKKCNH2 | |
| SCHEMBL2645293 | 0.80 | GCK (0.74) | FFAR2GCKKCNH2 | |
| SCHEMBL2645871 | 0.80 | GCK (0.74) | FFAR2GCKKCNH2 | |
| SCHEMBL2659048 | 0.80 | GCK (0.77) | FFAR2GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001083465-A2 | ALKYNYL PHENYL HETEROAROMATIC GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-08 | — | — | WO | disclosed |