Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 9/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622850 | 1.00 | CSNK1E (0.42) | CSNK1ECFTRCSNK1DGALR2GALR1 | |
| SCHEMBL26645587 | 0.90 | CFTR (0.42) | CSNK1ECFTRCSNK1DSMPD3GPR119 | |
| SCHEMBL30622740 | 0.90 | CFTR (0.42) | CSNK1ECFTRCSNK1DSMPD3GPR119 | |
| SCHEMBL26645275 | 0.89 | CSNK1E (0.43) | CSNK1ECSNK1DGPR119PDE4APDE4B | |
| SCHEMBL30622919 | 0.88 | CSNK1E (0.46) | CSNK1ECSNK1DGPR119 | |
| SCHEMBL26645204 | 0.88 | CSNK1E (0.46) | CSNK1ECSNK1DGPR119 | |
| SCHEMBL26645681 | 0.86 | CSNK1E (0.48) | CSNK1ECSNK1DGPR119 | |
| SCHEMBL30622425 | 0.86 | CSNK1E (0.42) | CSNK1ECSNK1DKDM1APDE4APDE4B | |
| SCHEMBL26644880 | 0.86 | CSNK1E (0.42) | CSNK1ECSNK1DKDM1APDE4APDE4B | |
| SCHEMBL30623018 | 0.85 | CSNK1E (0.44) | CSNK1ECFTRCSNK1DGALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |