Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622740 | 1.00 | CFTR (0.42) | CFTRCSNK1ECSNK1DPGK1PDE4A | |
| SCHEMBL26645014 | 0.91 | CSNK1E (0.43) | CSNK1ECSNK1DGPR119 | |
| SCHEMBL30622825 | 0.91 | CSNK1E (0.43) | CSNK1ECSNK1DGPR119 | |
| SCHEMBL26645016 | 0.90 | CSNK1E (0.42) | CFTRCSNK1ECSNK1DPDE4APDE4B | |
| SCHEMBL30622850 | 0.90 | CSNK1E (0.42) | CFTRCSNK1ECSNK1DPDE4APDE4B | |
| SCHEMBL26645805 | 0.88 | CSNK1E (0.42) | CSNK1ECSNK1DGPR119 | |
| SCHEMBL26645275 | 0.87 | CSNK1E (0.43) | CSNK1ECSNK1DPDE4APDE4BPDE4C | |
| SCHEMBL30622922 | 0.86 | CSNK1E (0.43) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL26645443 | 0.86 | CSNK1E (0.43) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL26645019 | 0.86 | CSNK1D (0.47) | CSNK1ECSNK1DMAPK14CACNB4CACNA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |