Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 4/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 2/20 | 0.39 |
| ▸ | SKP1 | P63208 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623035 | 0.94 | CSNK1D (0.43) | CSNK1DCSNK1EMEN1KMT2AGPR119 | |
| SCHEMBL26645250 | 0.91 | CSNK1D (0.48) | CSNK1DCSNK1EGPR119CKS1BSKP1 | |
| SCHEMBL26645466 | 0.91 | CSNK1D (0.49) | CSNK1DCSNK1EGPR119POLBCKS1B | |
| SCHEMBL30622922 | 0.90 | CSNK1E (0.43) | CSNK1DCSNK1EMEN1KMT2AMAPK11 | |
| SCHEMBL26645443 | 0.90 | CSNK1E (0.43) | CSNK1DCSNK1EMEN1KMT2AMAPK11 | |
| SCHEMBL26645681 | 0.90 | CSNK1E (0.48) | CSNK1DCSNK1EGPR119MAPK11MAPK14 | |
| SCHEMBL26645014 | 0.89 | CSNK1E (0.43) | CSNK1DCSNK1EMEN1KMT2AGPR119 | |
| SCHEMBL30622825 | 0.89 | CSNK1E (0.43) | CSNK1DCSNK1EMEN1KMT2AGPR119 | |
| SCHEMBL26645399 | 0.89 | CSNK1E (0.46) | CSNK1DCSNK1EMEN1KMT2AGPR119 | |
| SCHEMBL26645705 | 0.89 | CSNK1D (0.46) | CSNK1DCSNK1EGPR119MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |