Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 7/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.38 |
| ▸ | SKP1 | P63208 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645681 | 0.91 | CSNK1E (0.48) | CSNK1DCSNK1EGPR119MAPK14CKS1B | |
| SCHEMBL26645250 | 0.90 | CSNK1D (0.48) | CSNK1DCSNK1EGPR119CKS1BSKP1 | |
| SCHEMBL26645466 | 0.90 | CSNK1D (0.49) | CSNK1DCSNK1EGPR119CKS1BSKP1 | |
| SCHEMBL26645522 | 0.90 | CSNK1E (0.44) | CSNK1DCSNK1EMAPTGPR119CKS1B | |
| SCHEMBL26645019 | 0.89 | CSNK1D (0.47) | CSNK1DCSNK1EGPR119MAPK14CKS1B | |
| SCHEMBL26645150 | 0.89 | CSNK1E (0.44) | CSNK1DCSNK1EMAPTGPR119HDAC4 | |
| SCHEMBL26645342 | 0.89 | CSNK1E (0.45) | CSNK1DCSNK1EMAPTGPR119CKS1B | |
| SCHEMBL26645412 | 0.88 | CSNK1E (0.42) | CSNK1DCSNK1EMAPTGPR119ENPP2 | |
| SCHEMBL26645399 | 0.88 | CSNK1E (0.46) | CSNK1DCSNK1EMAPTGPR119SRC | |
| SCHEMBL26645053 | 0.87 | CSNK1D (0.46) | CSNK1DCSNK1EGPR119CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |