Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26645592 | 0.88 | MAPK14 (0.45) | MAPK14CSNK1DCSNK1EBRAFKDR | |
| SCHEMBL26645659 | 0.80 | BRAF (0.46) | MAPK14CSNK1DCSNK1ECSNK1A1BRAF | |
| Hydrochloric Acid SCHEMBL26645698 | 0.79 | BRAF (0.46) | MAPK14CSNK1DCSNK1ECSNK1A1BRAF | |
| Hydrochloric Acid SCHEMBL26645132 | 0.79 | MAPK14 (0.45) | MAPK14BRAFKDRMAPK11SRC | |
| Hydrochloric Acid SCHEMBL26645137 | 0.79 | MAPK14 (0.45) | MAPK14BRAFKDRHTR3AMAPK11 | |
| SCHEMBL24554415 | 0.78 | MAPK14 (0.53) | MAPK14CSNK1DCSNK1ECSNK1A1BRAF | |
| Hydrochloric Acid SCHEMBL26645368 | 0.77 | MAPK14 (0.52) | MAPK14CSNK1DCSNK1ECSNK1A1BRAF | |
| Hydrochloric Acid SCHEMBL26645048 | 0.77 | MAPK14 (0.43) | MAPK14CSNK1DCSNK1EBRAFKDR | |
| Hydrochloric Acid SCHEMBL26645169 | 0.76 | PTGS2 (0.39) | MAPK14BRAFKDRHTR3ASRC | |
| SCHEMBL26645228 | 0.76 | SRC (0.43) | MAPK14BRAFKDRMAPK11SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |