Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645126 | 1.00 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645732 | 1.00 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL30622844 | 0.82 | AAK1 (0.36) | — | |
| SCHEMBL30622727 | 0.82 | AAK1 (0.36) | — | |
| SCHEMBL26645085 | 0.81 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645145 | 0.81 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645096 | 0.81 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645325 | 0.80 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645326 | 0.80 | APAF1 (0.38) | APAF1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26645555 | 0.74 | APAF1 (0.36) | APAF1LMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |