Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 8/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CPS1 | P31327 | 2/20 | 0.37 |
| ▸ | GALR2 | O43603 | 1/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645116 | 0.90 | CYP3A4 (0.45) | CSNK1ECSNK1DRORCGPR119 | |
| SCHEMBL26645412 | 0.88 | CSNK1E (0.42) | CSNK1ECSNK1DRORCGPR119 | |
| SCHEMBL30623117 | 0.87 | CSNK1E (0.41) | CSNK1ECSNK1DRORCGPR119BTK | |
| SCHEMBL26645531 | 0.87 | CSNK1E (0.49) | CSNK1ECSNK1DRORCGPR119BTK | |
| SCHEMBL26645399 | 0.86 | CSNK1E (0.46) | CSNK1ECSNK1DGPR119ALDH1A1HTT | |
| SCHEMBL26645082 | 0.86 | RYR2 (0.41) | CSNK1ECSNK1DCPS1PDE4APDE4B | |
| SCHEMBL26645379 | 0.86 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL30622835 | 0.86 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL30622820 | 0.85 | CYP3A4 (0.43) | CSNK1ECSNK1DRORCGPR119 | |
| SCHEMBL26645098 | 0.85 | CYP3A4 (0.43) | CSNK1ECSNK1DRORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |