Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 11/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 9/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622820 | 1.00 | CYP3A4 (0.43) | CYP3A4CYP3A5CSNK1ECSNK1DRORC | |
| SCHEMBL26645116 | 0.94 | CYP3A4 (0.45) | CYP3A4CYP3A5CSNK1ECSNK1DRORC | |
| SCHEMBL26645207 | 0.89 | CSNK1D (0.42) | CYP3A4CYP3A5CSNK1ECSNK1DRORC | |
| SCHEMBL26645531 | 0.89 | CSNK1E (0.49) | CSNK1ECSNK1DRORCGPR119 | |
| SCHEMBL26645019 | 0.88 | CSNK1D (0.47) | CYP3A4CYP3A5CSNK1ECSNK1DMEN1 | |
| SCHEMBL30623117 | 0.88 | CSNK1E (0.41) | CYP3A4CYP3A5CSNK1ECSNK1DRORC | |
| SCHEMBL26645283 | 0.87 | CSNK1D (0.40) | CYP3A4CYP3A5CSNK1ECSNK1DRORC | |
| SCHEMBL30623074 | 0.86 | CSNK1E (0.41) | CYP3A4CYP3A5CSNK1ECSNK1DRORC | |
| SCHEMBL26645275 | 0.86 | CSNK1E (0.43) | CYP3A4CYP3A5CSNK1ECSNK1DRORC | |
| SCHEMBL30622922 | 0.86 | CSNK1E (0.43) | CYP3A4CYP3A5CSNK1ECSNK1DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |