Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.62 |
| ▸ | SCD | O00767 | 2/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580537 | 0.88 | KDR (0.61) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL27727733 | 0.86 | SMN1; SMN2 (0.55) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL2370632 | 0.84 | CYP1A2 (0.58) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL31706355 | 0.84 | SCD (0.55) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL3584763 | 0.82 | KDR (0.57) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL31705888 | 0.81 | LMNA (0.56) | SCDNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL4716373 | 0.81 | MAPK14 (0.59) | LCKNPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL1270133 | 0.81 | SMN1; SMN2 (0.75) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL836669 | 0.81 | KDR (0.68) | KDRCCNE1CDK2CDK5SCD | |
| SCHEMBL10252594 | 0.81 | KDR (1.00) | KDRCCNE1CDK2CDK5SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215188-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PKMYT1 | MY-T BIO LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |
| CN-101492416-B | compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2012-02-22 | — | — | CN | disclosed |
| US-7951830-B2 | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | disclosed |
| CN-101704797-A | compounds effecting glucokinase | ASTRAZANECA AB | 2010-05-12 | — | — | CN | disclosed |
| US-20090227592-A1 | COMPOUNDS EFFECTING GLUCOKINASE | ASTRAZENECA AB (SE) | 2009-09-10 | — | — | US | disclosed |
| CN-101492416-A | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2009-07-29 | — | — | CN | disclosed |
| US-7524957-B2 | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2009-04-28 | — | — | US | disclosed |
| US-20080207636-A1 | Compounds Effecting Glucokinase | ASTRAZENECA AB (SE) | 2008-08-28 | — | — | US | disclosed |
| US-7390908-B2 | Such as 2-[3,5-Di(2-chlorobenzyloxy)benzoyl)amino]-thiazole; for treatment of diabetes | ASTRAZENECA AB (SE) | 2008-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207636-A1 | Compounds Effecting Glucokinase | GCKR, GCK, SLC5A2 | KDR 1821/4885CCNE1 816/4885CDK2 142/4885 |
| US-20090227592-A1 | COMPOUNDS EFFECTING GLUCOKINASE | GCKR, GCK, SLC5A2 | KDR 1821/4885CCNE1 816/4885CDK2 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.