Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645657 | 1.00 | SMO (0.40) | SMOCSNK1ECSNK1DKCNK3GRM5 | |
| SCHEMBL26645225 | 0.88 | SMO (0.40) | SMOGRM5 | |
| SCHEMBL26645067 | 0.88 | SMO (0.40) | SMOGRM5 | |
| SCHEMBL26645185 | 0.87 | SMO (0.43) | SMOKCNK3P2RX7 | |
| SCHEMBL26645392 | 0.87 | SMO (0.43) | SMOKCNK3P2RX7 | |
| SCHEMBL30622940 | 0.85 | CSNK1D (0.37) | SMOCSNK1ECSNK1DKCNK3GRM5 | |
| SCHEMBL30622815 | 0.85 | CSNK1D (0.37) | SMOCSNK1ECSNK1DKCNK3GRM5 | |
| SCHEMBL26645086 | 0.77 | CSNK1E (0.39) | SMOCSNK1ECSNK1DGRM5P2RX7 | |
| SCHEMBL26645369 | 0.76 | — | — | |
| SCHEMBL26645373 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |