Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622940 | 1.00 | CSNK1D (0.37) | CSNK1DCSNK1ETGFBR1KCNK3HDAC1 | |
| SCHEMBL30622988 | 0.90 | NR1H2 (0.39) | SETD7SMO | |
| SCHEMBL30622801 | 0.90 | NR1H2 (0.39) | SETD7SMO | |
| SCHEMBL30622883 | 0.90 | KCNK3 (0.42) | KCNK3SETD7SMO | |
| SCHEMBL30622953 | 0.90 | KCNK3 (0.42) | KCNK3SETD7SMO | |
| SCHEMBL26645657 | 0.85 | SMO (0.40) | CSNK1DCSNK1EKCNK3GRM5SMO | |
| SCHEMBL26645470 | 0.85 | SMO (0.40) | CSNK1DCSNK1EKCNK3GRM5SMO | |
| SCHEMBL16711450 | 0.81 | CSNK1E (0.52) | CSNK1DCSNK1ETGFBR1HDAC1HDAC2 | |
| SCHEMBL17925729 | 0.80 | HDAC1 (0.37) | HDAC1HDAC2SETD7PDK2 | |
| SCHEMBL17936829 | 0.80 | HDAC1 (0.37) | HDAC1HDAC2SETD7PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |