Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623024 | 1.00 | MAPKAPK2 (0.42) | MAPKAPK2LMNADHODHABHD6DAGLA | |
| SCHEMBL30623001 | 0.90 | MAPKAPK2 (0.41) | MAPKAPK2DHODHCDC7PIM1PIM2 | |
| SCHEMBL26645499 | 0.90 | MAPKAPK2 (0.41) | MAPKAPK2DHODHCDC7PIM1PIM2 | |
| SCHEMBL18350261 | 0.90 | MAPKAPK2 (0.42) | MAPKAPK2LMNADHODHABHD6DAGLA | |
| SCHEMBL30623019 | 0.81 | LMNA (0.43) | MAPKAPK2LMNAABHD6DAGLACDC7 | |
| SCHEMBL26645782 | 0.81 | LMNA (0.43) | MAPKAPK2LMNAABHD6DAGLACDC7 | |
| SCHEMBL30623046 | 0.80 | DHODH (0.38) | LMNADHODHABHD6DAGLA | |
| SCHEMBL26645297 | 0.80 | DHODH (0.38) | LMNADHODHABHD6DAGLA | |
| SCHEMBL18350447 | 0.75 | MAPKAPK2 (0.41) | MAPKAPK2LMNACDC7PIM1PIM2 | |
| SCHEMBL25225960 | 0.73 | PIK3C3 (0.55) | MAPKAPK2CDC7PIM1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |