SCHEMBL26646355

SCHEMBL26646355

CO[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)nc(C)nc21

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 8/20 0.64
ADORA2B P29275 7/20 0.64
ADORA3 P0DMS8 1/20 0.60
ADORA1 P30542 1/20 0.60
LMNA P02545 1/20 0.59
NT5E P21589 1/20 0.59
HIF1A Q16665 1/20 0.59
RNASEL Q05823 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626875 1.00 ADORA2A (0.64) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL8620940 0.92 ADORA2A (0.64) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL8619503 0.91 ADORA2A (0.58) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL1527213 0.90 ADORA2A (0.66) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL12150807 0.90 ADORA2A (0.66) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL29100469 0.90 ADORA2A (0.66) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL12300482 0.90 ADORA2A (0.66) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL12031300 0.90 ADORA2A (0.66) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL1527211 0.90 ADORA2A (0.66) ADORA2AADORA2BADORA3ADORA1LMNA
SCHEMBL29533297 0.90 ADORA2A (0.66) ADORA2AADORA2BADORA3ADORA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023217209-A1 DOUBLE-STRANDED RNA MOLECULE AND PHARMACEUTICAL USE THEREOF 澳门科技大学 2023-11-16 WO claimed
CN-114875027-A Double-stranded RNA molecule and medical application thereof 澳门科技大学 2022-08-09 CN claimed
US-20250304965-A1 DOUBLE-STRANDED RNA MOLECULE AND PHARMACEUTICAL USE THEREOF MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-10-02 US disclosed
US-20250230196-A1 MODIFIED SELF-REPLICATING MRNA Immorna (hangzhou) Biotechnology Co., Ltd. (CN) 2025-07-17 US disclosed
EP-4553164-A2 MODIFIED SELF-REPLICATING MRNA IMMORNA (HANGZHOU) BIOTECHNOLOGY CO., LTD. (CN) 2025-05-14 EP disclosed
WO-2023217209-A1 DOUBLE-STRANDED RNA MOLECULE AND PHARMACEUTICAL USE THEREOF 澳门科技大学 2023-11-16 WO disclosed
CN-114875027-A Double-stranded RNA molecule and medical application thereof 澳门科技大学 2022-08-09 CN disclosed