Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.58 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620940 | 0.91 | ADORA2A (0.64) | ADORA2AADORA2BRNASELADORA3ADORA1 | |
| SCHEMBL26646355 | 0.91 | ADORA2A (0.64) | ADORA2AADORA2BRNASELADORA3ADORA1 | |
| SCHEMBL8626875 | 0.91 | ADORA2A (0.64) | ADORA2AADORA2BRNASELADORA3ADORA1 | |
| SCHEMBL9413266 | 0.85 | ADORA3 (0.56) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL8672670 | 0.84 | ADORA3 (0.67) | ADORA2AADORA2BADORA3ADORA1HIF1A | |
| SCHEMBL8621803 | 0.84 | ADORA3 (0.67) | ADORA2AADORA2BADORA3ADORA1HIF1A | |
| SCHEMBL20870832 | 0.84 | ADORA3 (0.67) | ADORA2AADORA2BADORA3ADORA1HIF1A | |
| SCHEMBL8621751 | 0.83 | ADORA2A (0.64) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL8621759 | 0.83 | ADORA2A (0.64) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| 2-Methyladenosine SCHEMBL13403859 | 0.83 | LMNA (0.75) | ADORA2AADORA2BADORA3ADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773603-A | ADENOSINE DEAMINASE INHIBITOR | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| US-5705491-A | Adenosine deaminase inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0601322-A2 | Adenosindeaminase inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |