⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3448931 | 0.98 | KDM4E (0.51) | — | |
| SCHEMBL11395633 | 0.98 | KDM4E (0.51) | — | |
| Lithium SCHEMBL29505670 | 0.98 | KDM4E (0.51) | — | |
| SCHEMBL2100653 | 0.82 | — | — | |
| SCHEMBL2588734 | 0.80 | — | — | |
| Potassium Ion SCHEMBL11400680 | 0.78 | GABRR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL11004255 | 0.78 | GABRR1 (0.44) | — | |
| SCHEMBL11395637 | 0.78 | GABRR1 (0.44) | — | |
| SCHEMBL7104572 | 0.77 | GAA (0.54) | — | |
| SCHEMBL1498468 | 0.77 | BCAT2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4063023-A | Process for preparing 4-(hydroxymethyl)imidazole compounds | SK&F LAB CO. (US) | 1977-12-13 | — | — | US | claimed |
| US-20240175141-A1 | BIOBASED AND BIODEGRADABLE CORROSION INHIBITION COMPOSITION | ZestBio, Inc. | 2024-05-30 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3969439-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |
| US-10377739-B2 | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) | 2019-08-13 | — | — | US | disclosed |
| CN-109715609-A | Cyclohexylbenzoyl amine compounds | 伊莱利利公司 | 2019-05-03 | — | — | CN | disclosed |
| US-20190084961-A1 | Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) | 2019-03-21 | — | — | US | disclosed |
| US-10196377-B2 | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) | 2019-02-05 | — | — | US | disclosed |
| US-20180022728-A1 | Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) | 2018-01-25 | — | — | US | disclosed |
| US-4743586-A | PREPARATION FROM A METHYLAMINE, 2-OXIME OF ETHYL 2,3-DIOXOBUTYRATE, HYDRAZINE, TRIETHOXYMETHANE | AMERICAN CYANAMID COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0049638-B1 | PROCESS FOR PREPARARING 5-METHYL-4-IMIDAZOLECARBOXYLIC ACID ESTERS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0189458-A1 | IMIDAZOLE PLANT GROWTH REGULATORS | FMC Corporation (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4565875-A | Imidazole plant growth regulators | FMC CORPORATION (US) | 1986-01-21 | — | — | US | disclosed |
| WO-1986000305-A1 | IMIDAZOLE PLANT GROWTH REGULATORS | FMC CORPORATION (US) | 1986-01-16 | — | — | WO | disclosed |
| US-4539331-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | LABORATORIOS VITA, S.A. (ES) | 1985-09-03 | — | — | US | disclosed |
| US-4374252-A | Benzyl 5-methyl-4-imidazolecarboxylate | SK&F LAB CO. (US) | 1983-02-15 | — | — | US | disclosed |
| US-4328349-A | Process for preparing 5-methyl-4-imidazolecarboxylic acid esters | SK&F LAB CO. (US) | 1982-05-04 | — | — | US | disclosed |
| EP-0049638-A1 | Process for prepararing 5-methyl-4-imidazolecarboxylic acid esters | SMITHKLINE BECKMAN CORPORATION (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4055573-A | TO 4-HYDROXYMETHYL OR ALKOXYMETHYL IMIDAZOLES | SMITHKLINE CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |