Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.90 |
| ▸ | BCL2 | P10415 | 19/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26648056 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL31450980 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL26648063 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL26648227 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL26648216 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL31451153 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL30857628 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2 | |
| SCHEMBL26647869 | 0.95 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL31450771 | 0.95 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL26648502 | 0.95 | BCL2L1 (0.85) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092057-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-02 | — | — | US | disclosed |
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092057-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | BCL2L2, BCL2A1, BCL2L1 | BCL2L1 3/4885BCL2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.