Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | APOB | P04114 | 1/20 | 0.41 |
| ▸ | MTTP | P55157 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | USP36 | Q9P275 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11895489 | 1.00 | CA1 (0.50) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11444221 | 0.85 | CA1 (0.61) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4782371 | 0.84 | CA1 (0.52) | CA1CA2CA12CA7CA14 | |
| SCHEMBL22469092 | 0.84 | PNMT (0.40) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11896240 | 0.81 | CA1 (0.49) | CA1CA2CA12CA7CA14 | |
| SCHEMBL21061713 | 0.79 | AHR (0.51) | GRM7HDAC8 | |
| SCHEMBL20791258 | 0.79 | CA1 (0.44) | CA1CA2CA12CA7CA14 | |
| SCHEMBL1590871 | 0.79 | CA1 (0.44) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4641731 | 0.79 | CA1 (0.47) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11898609 | 0.79 | GRM7 (0.46) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218203-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |