Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | GIPR | P48546 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915272 | 0.91 | GCGR (0.50) | GCGRGIPRIGF2BP2MAPK14TRPV1 | |
| SCHEMBL2664966 | 0.91 | GCGR (0.50) | GCGRGIPRIGF2BP2MAPK14TRPV1 | |
| SCHEMBL2665153 | 0.87 | GCGR (0.50) | GCGRGPR139GIPRGLP1R | |
| SCHEMBL2665057 | 0.84 | GCGR (0.43) | GCGRGIPRMAPK14TRPV1 | |
| SCHEMBL9071434 | 0.81 | GCGR (0.55) | GCGRGIPRTRPV1 | |
| SCHEMBL2665058 | 0.81 | GCGR (0.51) | GCGRGIPRTRPV1GLP1R | |
| SCHEMBL2664967 | 0.80 | GCGR (0.57) | GCGRGIPRTRPV1GLP1R | |
| SCHEMBL6916108 | 0.80 | GCGR (0.57) | GCGRGIPRTRPV1GLP1R | |
| SCHEMBL2665132 | 0.79 | GCGR (0.54) | GCGRGIPRIGF2BP2MAPK14TRPV1 | |
| SCHEMBL2665131 | 0.78 | GCGR (0.46) | GCGRGPR139GIPRROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |