Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.42 |
| ▸ | GIPR | P48546 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665119 | 0.91 | GCGR (0.51) | GCGRMAPK14IGF2BP2GIPRTRPV1 | |
| SCHEMBL2647008 | 0.91 | GCGR (0.51) | GCGRMAPK14IGF2BP2GIPRTRPV1 | |
| SCHEMBL2647002 | 0.91 | GCGR (0.51) | GCGRMAPK14IGF2BP2GIPRTRPV1 | |
| SCHEMBL2665135 | 0.86 | GCGR (0.47) | GCGRROCK2ROCK1MAPK14GPR139 | |
| SCHEMBL2665137 | 0.86 | GCGR (0.47) | GCGRROCK2ROCK1MAPK14GPR139 | |
| SCHEMBL2665161 | 0.86 | GCGR (0.51) | GCGRROCK2ROCK1MAPK14IGF2BP2 | |
| SCHEMBL2665047 | 0.84 | GCGR (0.45) | GCGRMAPK14GIPRTRPV1EPHX2 | |
| SCHEMBL9071437 | 0.81 | GCGR (0.58) | GCGRGIPRTRPV1EPHX2 | |
| SCHEMBL2665219 | 0.80 | GCGR (0.58) | GCGRGIPRTRPV1EPHX2 | |
| SCHEMBL6917347 | 0.80 | GCGR (0.58) | GCGRGIPRTRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |