Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660801 | 0.77 | CA12 (0.56) | CA12CA9F11CA1CA3 | |
| SCHEMBL15448608 | 0.74 | CA12 (0.58) | CA12CA9F11CA1CA3 | |
| SCHEMBL29496155 | 0.74 | CA12 (0.49) | CA12CA9F11CA1CA3 | |
| SCHEMBL2171366 | 0.71 | CA12 (0.55) | CA12CA9F11CA1CA3 | |
| SCHEMBL9267952 | 0.71 | CA12 (0.53) | CA12CA9F11CA1CA3 | |
| SCHEMBL20563183 | 0.71 | CA12 (0.48) | CA12CA9F11CA1CA3 | |
| SCHEMBL25376998 | 0.70 | CA12 (0.41) | CA12CA9HCAR1 | |
| SCHEMBL30482242 | 0.70 | CA12 (0.41) | CA12CA9HCAR1 | |
| SCHEMBL29026906 | 0.70 | CA12 (0.53) | CA12CA9F11CA1CA3 | |
| SCHEMBL26650719 | 0.69 | CA12 (0.47) | CA12CA9F11CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-119212988-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |