Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267952 | 0.83 | CA12 (0.53) | CA12CA9HCAR1F11DAO | |
| SCHEMBL2820360 | 0.79 | CA12 (0.58) | CA12CA9HCAR1F11CA1 | |
| SCHEMBL6370054 | 0.79 | CA12 (0.49) | CA12CA9HCAR1F11DAO | |
| SCHEMBL2171366 | 0.76 | CA12 (0.55) | CA12CA9HCAR1F11DAO | |
| SCHEMBL6378203 | 0.75 | CA12 (0.45) | CA12CA9EIF4A3 | |
| SCHEMBL20660801 | 0.74 | CA12 (0.56) | CA12CA9HCAR1F11DAO | |
| SCHEMBL26650601 | 0.74 | CA12 (0.47) | CA12CA9HCAR1F11CA1 | |
| SCHEMBL2165918 | 0.73 | CA12 (0.60) | CA12CA9F11DAODDO | |
| SCHEMBL29495976 | 0.71 | CA12 (0.41) | CA12CA9HCAR1AKR1B1AR | |
| SCHEMBL705402 | 0.71 | CA12 (0.62) | CA12CA9HCAR1F11DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |