Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.55 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.55 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.55 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.55 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.55 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.55 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.55 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.55 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.55 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647432 | 0.87 | GCG (0.54) | GCGRRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL2647438 | 0.87 | GCG (0.54) | GCGRRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL9071387 | 0.85 | GCGR (0.56) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2648150 | 0.84 | GCGR (0.53) | GCGRGIPR | |
| SCHEMBL2661127 | 0.84 | GCGR (0.57) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2655401 | 0.84 | GCGR (0.57) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2648042 | 0.84 | GCGR (0.53) | GCGRGIPR | |
| SCHEMBL2661122 | 0.84 | GCGR (0.57) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665070 | 0.84 | GCGR (0.47) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2655403 | 0.84 | GCGR (0.57) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |