Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.47 |
| ▸ | GIPR | P48546 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.39 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647087 | 0.87 | GCGR (0.47) | GCGRGIPRKCNK2KCNK10ADCY6 | |
| SCHEMBL2647091 | 0.87 | GCGR (0.47) | GCGRGIPRKCNK2KCNK10ADCY6 | |
| SCHEMBL9071390 | 0.85 | GCGR (0.42) | GCGRGIPRCHRM4KCNK2KCNK10 | |
| SCHEMBL2648042 | 0.84 | GCGR (0.53) | GCGRGIPR | |
| SCHEMBL2648152 | 0.84 | GCGR (0.53) | GCGRGIPR | |
| SCHEMBL2648150 | 0.84 | GCGR (0.53) | GCGRGIPR | |
| SCHEMBL2665067 | 0.84 | GCGR (0.55) | GCGRGIPREPHX2NR1H4ADCY6 | |
| SCHEMBL2647432 | 0.83 | GCG (0.54) | GCGRGIPRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2647438 | 0.83 | GCG (0.54) | GCGRGIPRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2647088 | 0.83 | GCGR (0.45) | GCGRGIPRCHRM4EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |