Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.47 |
| ▸ | GIPR | P48546 | 10/20 | 0.47 |
| ▸ | GLP1R | P43220 | 2/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648952 | 0.81 | GCGR (0.48) | GCGRGIPRSERPINE1BCL2L1MCL1 | |
| SCHEMBL2648950 | 0.81 | GCGR (0.48) | GCGRGIPRSERPINE1BCL2L1MCL1 | |
| SCHEMBL2665144 | 0.78 | GCGR (0.51) | GCGRGIPRGLP1RSERPINE1BCL2L1 | |
| SCHEMBL6916484 | 0.78 | GCGR (0.53) | GCGRGIPRGLP1RBCL2L1MCL1 | |
| SCHEMBL6916489 | 0.78 | GCGR (0.53) | GCGRGIPRGLP1RBCL2L1MCL1 | |
| SCHEMBL2645898 | 0.77 | GCGR (0.46) | GCGRGIPRSERPINE1BCL2L1MCL1 | |
| SCHEMBL2645893 | 0.77 | GCGR (0.46) | GCGRGIPRSERPINE1BCL2L1MCL1 | |
| SCHEMBL2665081 | 0.77 | GCGR (0.49) | GCGRGIPRGLP1RSERPINE1BCL2L1 | |
| SCHEMBL9071434 | 0.75 | GCGR (0.55) | GCGRGIPR | |
| SCHEMBL2659967 | 0.74 | GCGR (0.47) | GCGRGIPRGLP1RSERPINE1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |