Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.46 |
| ▸ | GIPR | P48546 | 8/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915810 | 0.88 | GCGR (0.47) | GCGRGIPRTAOK1TAOK3NPC1 | |
| SCHEMBL6910175 | 0.88 | GCGR (0.53) | GCGRGIPRTAOK1TAOK3RAB9A | |
| SCHEMBL2665138 | 0.88 | GCGR (0.47) | GCGRGIPRTAOK1TAOK3NPC1 | |
| SCHEMBL6910313 | 0.88 | GCGR (0.53) | GCGRGIPRTAOK1TAOK3RAB9A | |
| SCHEMBL6910310 | 0.88 | GCGR (0.53) | GCGRGIPRTAOK1TAOK3RAB9A | |
| SCHEMBL2665036 | 0.88 | GCGR (0.53) | GCGRGIPRTAOK1TAOK3RAB9A | |
| SCHEMBL9071500 | 0.85 | GCGR (0.47) | GCGRGIPRTAOK1TAOK3NPC1 | |
| SCHEMBL2648378 | 0.85 | CYP2D6 (0.44) | GCGRGIPRTAOK1TAOK3NPC1 | |
| SCHEMBL2648373 | 0.85 | CYP2D6 (0.44) | GCGRGIPRTAOK1TAOK3NPC1 | |
| SCHEMBL2647075 | 0.85 | CYP2D6 (0.44) | GCGRGIPRTAOK1TAOK3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |