Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.53 |
| ▸ | GIPR | P48546 | 11/20 | 0.53 |
| ▸ | GLP1R | P43220 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910310 | 1.00 | GCGR (0.53) | GCGRGIPRGLP1RGRIN2CPPARD | |
| SCHEMBL6910175 | 1.00 | GCGR (0.53) | GCGRGIPRGLP1RGRIN2CPPARD | |
| SCHEMBL2665036 | 1.00 | GCGR (0.53) | GCGRGIPRGLP1RGRIN2CPPARD | |
| SCHEMBL2665138 | 0.89 | GCGR (0.47) | GCGRGIPRPPARDRAB9APPARG | |
| SCHEMBL6915810 | 0.89 | GCGR (0.47) | GCGRGIPRPPARDRAB9APPARG | |
| SCHEMBL2665220 | 0.88 | GCGR (0.46) | GCGRGIPRPPARDRAB9APPARG | |
| SCHEMBL9071500 | 0.86 | GCGR (0.47) | GCGRGIPRRAB9ATAOK1TAOK3 | |
| SCHEMBL2646588 | 0.85 | GCGR (0.43) | GCGRGIPRPPARDALDH1A1HPGD | |
| SCHEMBL2646584 | 0.85 | GCGR (0.43) | GCGRGIPRPPARDALDH1A1HPGD | |
| SCHEMBL6910316 | 0.84 | RAB9A (0.38) | GCGRGIPRGRIN2CALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762318-B2 | CARBOXYLIC ACID OR TETRAZOLE DERIVATIZED SECONDARY AMIDES; ORAL ADMINISTRATION | NOVO NORDISK A/S (DK) | 2004-07-13 | — | — | US | disclosed |
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | PFIZER INC | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | GPR119, GLP1R, GIPR | GCGR 4/4885GIPR 3/4885GLP1R 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.