Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.60 |
| ▸ | GIPR | P48546 | 14/20 | 0.60 |
| ▸ | GLP1R | P43220 | 4/20 | 0.60 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071501 | 0.88 | GCGR (0.57) | GCGRGIPRGLP1R | |
| SCHEMBL9071502 | 0.86 | GCGR (0.51) | GCGRGIPRGLP1R | |
| SCHEMBL9071384 | 0.86 | GCGR (0.59) | GCGRGIPRGLP1RNPC1ALDH1A1 | |
| SCHEMBL9071436 | 0.84 | GCGR (0.43) | GCGRGIPRGLP1R | |
| SCHEMBL9071437 | 0.78 | GCGR (0.58) | GCGRGIPR | |
| SCHEMBL2651577 | 0.77 | GCGR (0.69) | GCGRGIPRGLP1RSERPINE1 | |
| SCHEMBL2654184 | 0.77 | GCGR (0.69) | GCGRGIPRGLP1RSERPINE1 | |
| SCHEMBL2652684 | 0.77 | GCGR (0.69) | GCGRGIPRGLP1RSERPINE1 | |
| SCHEMBL2651188 | 0.75 | GCGR (1.00) | GCGRGIPRGLP1R | |
| SCHEMBL2651186 | 0.75 | GCGR (1.00) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |