Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.51 |
| ▸ | GIPR | P48546 | 16/20 | 0.51 |
| ▸ | GLP1R | P43220 | 5/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071501 | 0.90 | GCGR (0.57) | GCGRGIPRGLP1REPHX2NR1H4 | |
| SCHEMBL2665235 | 0.86 | GCGR (0.60) | GCGRGIPRGLP1R | |
| SCHEMBL9071387 | 0.86 | GCGR (0.56) | GCGRGIPRGLP1REPHX2NR1H4 | |
| SCHEMBL2665128 | 0.85 | GCGR (0.56) | GCGRGIPR | |
| SCHEMBL2665091 | 0.83 | GCGR (0.42) | GCGRGIPRGLP1REPHX2NR1H4 | |
| SCHEMBL2665084 | 0.81 | GCGR (0.42) | GCGRGIPRGLP1R | |
| SCHEMBL6910175 | 0.80 | GCGR (0.53) | GCGRGIPRGLP1R | |
| SCHEMBL6910313 | 0.80 | GCGR (0.53) | GCGRGIPRGLP1R | |
| SCHEMBL6910310 | 0.80 | GCGR (0.53) | GCGRGIPRGLP1R | |
| SCHEMBL2665036 | 0.80 | GCGR (0.53) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |