Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657079 | 0.78 | FFAR2 (0.72) | FFAR2MAPTKCNH2GCK | |
| SCHEMBL2645075 | 0.78 | FFAR2 (0.72) | FFAR2MAPTKCNH2GCK | |
| SCHEMBL2645076 | 0.78 | FFAR2 (0.72) | FFAR2MAPTKCNH2GCK | |
| SCHEMBL14423127 | 0.76 | FFAR2 (0.57) | FFAR2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2642059 | 0.76 | FFAR2 (0.57) | FFAR2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2642244 | 0.76 | FFAR2 (0.59) | FFAR2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2660251 | 0.76 | FFAR2 (0.59) | FFAR2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2642146 | 0.75 | FFAR2 (0.56) | FFAR2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14423133 | 0.75 | FFAR2 (0.56) | FFAR2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2659463 | 0.75 | FFAR2 (0.67) | FFAR2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095438-A1 | SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-20 | — | — | WO | disclosed |